The diluent and pediatric NAC dosing

N-acetylcysteine is a well established and effective treatment for acetaminophen overdoses.  The 21hr  IV dosing and the 72hr oral regimens are also well studied and effective in preventing hepatic damage.  One often over-looked technical detail to administration of NAC occurs with pediatric patients.  There is a require dilution that is weight based for children that helps prevent electrolyte and fluid complications. The manufacturer provides a weight based dosing for pediatric patients.

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