A quick review of biologic immunomodulators. The various letters chosen in the name indicated the structure, origin, and targets of the molecule. For example ixekizumab for psoriasis ends with –mab, so it is a monoclonal antibody, has a –u- so it is human and has –ki- which means that it is interleukin targeted.
If your mobile app is crashing and lacking content, please uninstall and perform a full update upon re-install. The app needs to download the entire wiki and must be performed on wifi. Please do not let your phone sleep during the process as it will interrupt the download. Due to the size of the wiki we cannot perform a background update. If your phone did turn off the screen during setup please click the blue update button in the app and reattempt initial download. After this initial download, pages will only update if changes have occurred since last viewed.… Read more
If you newly installed the app or upgraded your phone and reinstalled the app and don’t see any content, connect to wifi and click the blue update button to download a fresh offline copy of the wiki. The app does not update on cellular by default to prevent data charges due to the size of the initial download that must occur for you to have the entire wiki offline… Read more
As winter is upon those in the United States, make sure you are treating your patients with pneumonia using the appropriate antibiotics. Outpatient treatment is divided among those with significant comorbidities and those without. The inpatient regimens distinguish between hospital associated, community acquired and those requiring the ICU.… Read more
One of the newest drugs available to some EM provider is Sugammadex. Trade name, Bridion, the drug functions as a reversal agent for Rocuronium. An IV bolus of 16 mg/kg over 10 seconds via a central or peripheral line will reverse a single 1.2 mg/kg dose of rocuronium in approximately 3 minutes. Although rarely used in the emergent setting, keep the dose in the back of your mind or reference on the WikEM app just incase you need to order it.… Read more